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The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. Levitra may uncommonly cause mild, temporary vision changes (eg, blurred vision, sensitivity to levitra liver blue/green color tint to vision). In some patients the use of PDE5 inhibitor drugs, including Levitra, with alpha-blockers can lower blood pressure significantly leading to fainting. Cardura (doxazosin mesylate) is a trademark of Pfizer Inc. Safety of combined use of PDE5 inhibitors and alpha-blockers may be affected by other variables, including intravascular volume depletion and other anti-hypertensive drugs. Other CYP3A4 inhibitors: Although specific interactions have not been studied, other CYP3A4 inhibitors, including grapefruit juice would likely increase vardenafil exposure. In those patients levitra liver taking an optimized dose of PDE5 inhibitor, alpha-blocker therapy should be initiated at the lowest dose. Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Vardenafil HCl levitra liver designated chemically as piperazine, 1--4-ethyl-, monohydrochloride and has the following structural formula: Vardenafil HCl is a nearly colorless, solid substance with a molecular weight of 579.1 g/mol and a solubility of 0.11 mg/mL in water. Your doctor may lower your dose or raise your dose, depending on how your body reacts to Levitra. Revision Date: 01/25/2010 12:14:25 PM. Before using Levitra: Some medical conditions may interact with Levitra. You may report side effects to FDA at 1-800-FDA-1088. FDA pregnancy category B: Although Levitra is not for use in women, this medication is not expected to be harmful to an unborn baby. Levitra is not recommended for use in CHILDREN; safety and effectiveness in children have not been confirmed. In these studies systemic drug exposures (AUCs) for unbound (free) vardenafil and its major metabolite were approximately 400- and 170-fold for male and female rats, respectively, and 21- and 37-fold for male and female mice, respectively, the exposures observed in human males given the Maximum Recommended Human Dose (MRHD) of 20 mg. Nifedipine did not alter the plasma levitra liver of Levitra when taken in combination.    BODY AS A WHOLE: anaphylactic reaction (including laryngeal edema),    asthenia, face edema, pain    AUDITORY: sudden decrease or loss of hearing, tinnitus    CARDIOVASCULAR: angina pectoris, chest pain, hypertension,    hypotension, myocardial ischemia, myocardial infarction, palpitation,    postural hypotension, syncope, tachycardia    DIGESTIVE: abdominal pain, abnormal liver function tests, diarrhea, levitra liver    mouth, dysphagia, esophagitis, gastritis, gastroesophageal reflux, GGTP    increased, vomiting    MUSCULOSKELETAL: arthralgia, back pain, myalgia, neck pain    NERVOUS: hypertonia, hypesthesia, insomnia, paresthesia, somnolence,    vertigo    RESPIRATORY: dyspnea, epistaxis, pharyngitis    SKIN AND APPENDAGES: photosensitivity reaction, pruritus, rash,    sweating    OPHTHALMOLOGIC: abnormal vision, blurred vision, chromatopsia,    changes in color vision, conjunctivitis (increased redness of the eye), dim    vision, eye pain, glaucoma, photophobia, watery eyes    UROGENITAL: abnormal ejaculation, priapism (including prolonged or    painful erections) POST-MARKETING EXPERIENCE Ophthalmologic Non-arteritic anterior ischemic optic neuropathy (NAION), a levitra liver of decreased vision including permanent loss of vision, has been reported rarely post-marketing in temporal association with the use of phosphodiesterase type 5 (PDE5) inhibitors, including Levitra. During sexual stimulation, nitric oxide is released from nerve endings and endothelial cells in the corpus cavernosum. Call your doctor for medical advice about side effects. Two of these trials were conducted in the general ED population and two in special ED populations (one in patients with diabetes mellitus and one in post-prostatectomy patients).

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