can lipitor be cut in half
Lipitor can lower the risk for heart attack, stroke, certain types of heart surgery, and chest pain in patients who have heart disease or risk factors for heart disease such as: age, smoking, high blood pressure, low HDL-C, can lipitor be cut in half disease in the family. It is used along with an appropriate diet. Follow the directions on your prescription label. 2.6 Dosage in Patients Taking can lipitor be cut in half Clarithromycin, Itraconazole, or a Combination of Ritonavir plus Saquinavir or Lopinavir plus Ritonavir In patients taking cyclosporine, therapy should be limited to Lipitor 10 mg once daily. Atorvastatin may pass into breast milk and could harm a nursing baby. Lipitor will not be as effective can lipitor be cut in half lowering your cholesterol if you do not follow a cholesterol-lowering diet plan. Tell your doctor about all medications you use. In patients with Fredrickson Types IIa and IIb hyperlipoproteinemia pooled from 24 controlled trials, the median (25th and 75th percentile) percent changes from baseline in HDL-C for Lipitor 10, 20, 40, and 80 mg were 6.4 (-1.4, 14), 8.7 (0, 17), 7.8 (0, 16), and 5.1 (-2.7, 15), respectively. Mean Percentage Change From Baseline at Endpoint (Double-Blind, Randomized, Active-Controlled Trials) Treatment Non-HDL-C/ (Daily Dose) N Total-C LDL-C Apo B TG HDL-C HDL-C Study 1 Lipitor 10 mg 707 -27* -36* -28* -17* +7 -37* Lovastatin 20 mg 191 -19 -27 -20 -6 +7 -28 95% CI for Diff† -9.2, -6.5 -10.7, -7.1 -10.0, -6.5 -15.2, -7.1 -1.7, 2.0 -11.1, -7.1 Study 2 Lipitor 10 mg 222 -25‡ -35‡ -27‡ -17‡ +6 -36‡ Pravastatin 20 mg 77 -17 -23 -17 -9 +8 -28 95% CI for Diff† -10.8, -6.1 -14.5, -8.2 -13.4, -7.4 -14.1, -0.7 -4.9, 1.6 -11.5, -4.1 Study 3 Lipitor 10 mg 132 -29§ -37§ -34§ -23§ +7 -39§ Simvastatin 10 mg 45 -24 -30 -30 -15 +7 -33 95% CI for Diff† -8.7, -2.7 -10.1, -2.6 -8.0, -1.1 -15.1, -0.7 -4.3, 3.9 -9.6, -1.9 * Significantly different from lovastatin, ANCOVA, p ≤0.05 † A negative value for the 95% CI for the difference between treatments favors Lipitor for all except HDL-C, for which a positive value favors Lipitor. Table 2 summarizes the frequency of clinical can lipitor be cut in half reactions, regardless of causality, reported in ≥ 2% and at a rate greater than placebo in patients treated with Lipitor (n=8755), from seventeen placebo-controlled trials. Do not give Lipitor to other people, even if they have the same problem you have. Lipitor can lipitor be cut in half an HMG-CoA reductase inhibitor, also known as a "statin." It works by reducing the can lipitor be cut in half of certain fatty substances in the body, including cholesterol. 12.3 Pharmacokinetics Absorption: Lipitor is rapidly absorbed after oral administration; maximum plasma concentrations occur within 1 to 2 hours. Keep a list of all your medicines and show it to any healthcare provider who treats you. Postmarketing Experience The following adverse reactions have been identified during postapproval use of Lipitor. Seek medical attention right away if any of these SEVERE side effects occur: Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bone, joint, or tendon pain; change in the amount of urine produced; chest pain; dark urine; fever, chills, or persistent sore throat; flu-like symptoms; joint pain; muscle pain, tenderness, or weakness (with or without fever or fatigue); painful or can lipitor be cut in half urination; can lipitor be cut in half stools; red, swollen, blistered, or peeling skin; severe stomach pain; swelling of the hands, ankles, or feet; yellowing of the eyes or skin. Lipitor is for adults and children over 10 whose cholesterol does not come down enough with exercise and a low-fat diet alone. Do not take extra medicine to make up the missed dose.
What happens if I overdose?
Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.
What should I avoid while taking atorvastatin?
Avoid eating foods that are high in fat or can lipitor be cut in half Atorvastatin is an inhibitor of 3-hydroxy-3-methylglutaryl-coenzyme A (HMG-CoA) reductase. Do not take 2 doses of Lipitor at the same time. Triglycerides (TG) and cholesterol in the liver are incorporated into VLDL and released into the plasma for delivery to peripheral tissues. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Do not miss any doses. You may report side effects to FDA at 1-800-FDA-1088. Recommended dosage for Lipitor You need to follow a standard cholesterol-lowering diet before starting Lipitor, and should continue following it throughout your therapy. Report any unexplained muscle pain, tenderness, or weakness to your doctor right away, especially if you also have a fever or general body discomfort. Mean plasma elimination half-life of Lipitor in humans is approximately 14 hours, but the half-life of inhibitory activity for HMG-CoA reductase is 20 to 30 hours due to the contribution of active metabolites. The number of Lipitor-treated patients who required uptitration to 20 mg after Week 4 during the double-blind phase was 80 (57.1%). Hematologic Hematologic side effects including hemolytic anemia, thrombocytopenia, and leukopenia have occurred with HMG-CoA reductase inhibitors. Treatment with Lipitor 80 mg/day significantly reduced the rate of MCVE (434 events in the 80 mg/day group vs.
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