compare lipitor and lovastatin
In addition, at least one case of polyneuropathy attributed to atorvastatin use has also been reported. Check with your doctor if any of these most COMMON side effects persist or become bothersome: Constipation; gas; headache; stomach pain or upset; weakness. compare lipitor and lovastatin medical attention right away if any of these SEVERE side effects occur: Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bone, joint, or tendon pain; change in the amount of urine produced; chest pain; dark urine; fever, chills, or persistent sore throat; flu-like symptoms; joint pain; muscle pain, tenderness, or weakness (with or without fever or fatigue); painful or frequent urination; pale stools; red, swollen, blistered, or compare lipitor and lovastatin skin; severe stomach pain; swelling of the hands, ankles, or feet; yellowing of the eyes or skin. 374 (8.4%) in the simvastatin 20–40 mg/day group. 7.5 Digoxin When multiple doses of Lipitor and digoxin were coadministered, steady state plasma digoxin concentrations increased by approximately 20%. 2.4 Concomitant Lipid-Lowering Therapy Lipitor may be used compare lipitor and lovastatin compare lipitor and lovastatin acid resins. 39 events in the placebo group), HR 0.52, 95% CI (0.31, 0.89) (p=0.016) and reduced the risk of MI by 42% (38 events in the Lipitor group vs. Your doctor may prescribe Lipitor to reduce your chances of having a heart attack or developing heart disease compare lipitor and lovastatin you have any of the following risk factors: are age 55 years or older smoke have high blood pressure have low levels of HDL (high-density lipoprotein—the good cholesterol) have a family history compare lipitor and lovastatin early heart disease For people at high risk of heart disease, the doctor may suggest a cholesterol-lowering medication if LDL readings are 130 or more. How do I store Lipitor Store Lipitor at room temperature, 68 to 77°F (20 to 25°C). Serum cholesterol and triglycerides increase during normal pregnancy. Although food decreases the rate and extent of drug absorption by approximately 25% and 9%, respectively, as assessed by Cmax and AUC, LDL-C reduction is similar whether Lipitor is given with or without food. Therefore, in patients taking itraconazole, caution should be used when the Lipitor dose exceeds 20 mg .7.2 Grapefruit Juice Contains one or more components that inhibit CYP 3A4 and can increase plasma concentrations of atorvastatin, especially with excessive grapefruit juice consumption (>1.2 liters per day). Lipitor is effective in a wide variety of patient populations with hyperlipidemia, with and without hypertriglyceridemia, in men and women, and in the elderly. Effect of Atorvastatin on the Pharmacokinetics of Co-administered Drugs Atorvastatin Co-administered drug and dosing regimen Drug/Dose (mg) Change in AUC Change in Cmax 80 mg QD for 15 days Antipyrine, 600 mg SD ↑ 3% ↓ 11% 80 mg QD for 14 days * Digoxin 0.25 mg QD, 20 days ↑ 15% ↑ 20% 40 mg QD for 22 days Oral contraceptive QD, 2 months -norethindrone 1 mg -ethinyl estradiol 35µg ↑ 28% ↑ 19% ↑ 23% ↑ 30% * See Section 7 for clinical significance. If you miss a dose...
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