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Elevations of CK (≥ 10 × ULN) were low overall, but were higher in the high-dose atorvastatin treatment group (13, 0.3%) compared to the low-dose atorvastatin group (6, 0.1%). This includes prescription, over-the-counter, vitamin, and herbal products. Your doctor may prescribe Lipitor to reduce your chances of having a heart attack or developing heart disease if you have any of the following risk factors: are age 55 years or older smoke have high blood pressure have low levels of HDL (high-density lipoprotein—the good cholesterol) have a family history of early heart disease For people at high risk of heart disease, the doctor may suggest a cholesterol-lowering medication if LDL readings are 130 or more. In patients with CHD or multiple risk factors for CHD, Lipitor can be started simultaneously with diet. The absolute bioavailability of atorvastatin (parent drug) is approximately 14% and the systemic availability of HMG-CoA reductase inhibitory activity is approximately 30%. In patients with CHD or multiple risk factors for CHD, Lipitor can be started simultaneously with diet. Diabetes was reported as an adverse reaction in 144 subjects (6.1%) in the atorvastatin group and 89 subjects (3.8%) in the placebo group . 4.4 Nursing mothers It is not known whether atorvastatin is excreted into human milk; however a small amount of another drug in this class does pass into breast milk.

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