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lipitor or lovastatin

It can raise triglyceride levels and may increase your risk of liver damage. It can raise triglyceride levels and may increase your risk of liver damage. Grapefruit and grapefruit juice may interact with atorvastatin and lead to potentially dangerous effects. Atorvastatin calcium is . A 67-year-old women treated for hypercholesterolemia with atorvastatin developed myogenic lipitor or lovastatin and variable incomitant horizontal and vertical strabismus consistent with ocular myasthenia. lipitor or lovastatin Information About Lipitor Medicines are sometimes prescribed for conditions that are not mentioned in patient information leaflets. Lipitor should be used with extreme caution in CHILDREN younger than 10 years old and in those who have not reached puberty; safety and effectiveness in these children have not been confirmed.

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lipitor or lovastatin

A chemically similar drug in this class produced optic nerve degeneration (Wallerian degeneration of retinogeniculate fibers) in clinically normal dogs in a dose-dependent fashion at a dose that produced plasma drug levels about 30 times higher than the mean drug level in humans taking the highest recommended dose. Ptosis was present in both upper eyelids. Lipitor does make its way into breast milk, so you should not take the drug while breastfeeding your baby. Postmarketing Experience The following adverse reactions have been identified during postapproval use of Lipitor. Contraindications 4.1 Active liver disease, which may include unexplained persistent elevations in hepatic transaminase levels4.2 Hypersensitivity to any component of this medication4.3 Pregnancy Women who are pregnant or may become pregnant. Your doctor may occasionally lipitor or lovastatin your dose to make sure you get the best results. Do not break an atorvastatin lipitor or lovastatin 4.4 Nursing mothers It is not known whether atorvastatin is excreted into human milk; however a small amount of another drug in this class does pass into breast milk. Clinical and pathologic studies show that elevated plasma levels of total cholesterol (total-C), LDL-cholesterol (LDL-C), and apolipoprotein B (apo B) promote human atherosclerosis and are risk factors for developing cardiovascular disease, while increased levels of HDL-C are associated with a lipitor or lovastatin cardiovascular risk. Before taking Lipitor, tell your doctor if you have ever had liver or kidney disease, diabetes, or a thyroid disorder, or if you drink more than 2 alcoholic beverages daily. Take the medicine at the same time each day. Drug Interactions The risk of myopathy during treatment with statins is increased with concurrent administration of fibric acid derivatives, lipid-modifying doses of niacin, cyclosporine, or strong CYP 3A4 inhibitors (e.g., clarithromycin, HIV protease inhibitors, and itraconazole) . Stop taking Lipitor and tell your doctor right away if you become pregnant. Lipid-altering Effects of Lipitor in Adolescent Boys and Girls lipitor or lovastatin Heterozygous Familial Hypercholesterolemia or Severe Hypercholesterolemia (Mean Percentage Change From Baseline at Endpoint in Intention-to-Treat Population) DOSAGE N Total-C LDL-C HDL-C TG Apolipoprotein B Placebo 47 -1.5 -0.4 -1.9 1.0 0.7 Lipitor 140 -31.4 -39.6 2.8 -12.0 -34.0 The mean achieved LDL-C value was 130.7 mg/dL (range: 70.0–242.0 mg/dL) in the Lipitor group compared to 228.5 mg/dL (range: 152.0–385.0 mg/dL) in the placebo group during the 26-week double-blind phase. Serum cholesterol and triglycerides increase during normal pregnancy. In a review of about 100 prospectively followed pregnancies in women exposed to other statins, the incidences of congenital anomalies, spontaneous abortions, and fetal deaths/stillbirths did not exceed the rate expected in the general population. Avoid eating foods that lipitor or lovastatin high in fat or cholesterol. Use effective birth control to avoid pregnancy while you are taking Lipitor. Stroke Prevention by Aggressive Reduction in Cholesterol Levels (SPARCL) In SPARCL involving 4731 subjects (age range 21–92 years, 40% women; 93.3% Caucasians, 3.0% Blacks, 0.6% Asians, 3.1% other) without clinically evident CHD but with a stroke or transient ischemic attack (TIA) within the previous 6 months treated with Lipitor 80 mg (n=2365) or placebo (n=2366) for a median follow-up of 4.9 years, there was a higher incidence of persistent hepatic transaminase elevations (≥ 3 × ULN twice within 4–10 days) in the atorvastatin group (0.9%) compared to placebo (0.1%). Lipitor can be administered as a single dose at any time of the day, with or without food.