lipitor recommended dosage
Contraindications 4.1 Active liver disease, which may include unexplained persistent elevations in hepatic transaminase levels4.2 Hypersensitivity to any component of this medication4.3 Pregnancy Women who are pregnant or may become pregnant. Periodic creatine phosphokinase (CPK) determinations may be considered in such situations, but there is no assurance that such monitoring will prevent the occurrence of severe myopathy. Keep Lipitor and all medicines out of the reach of children. Lipitor - Clinical Pharmacology 12.1 Mechanism of Action Lipitor is a selective, competitive inhibitor of HMG-CoA reductase, the rate-limiting enzyme that converts 3-hydroxy-3-methylglutaryl-coenzyme A to mevalonate, a precursor of sterols, including lipitor recommended dosage Cmax and AUC are approximately lipitor recommended dosage and 11-fold increased, respectively, in patients with Childs-Pugh B disease involving 8,888 subjects (age range 26–80 years, 19% women; 99.3% Caucasians, 0.4% Asians, 0.3% Blacks, 0.04% other) treated with Lipitor 80 mg/day (n=4439) or simvastatin 20–40 mg daily (n=4449), there was no difference in the overall frequency of adverse reactions or serious lipitor recommended dosage reactions between the treatment groups during a median follow-up of 4.8 years. Top More Lipitor resources Lipitor Prescribing Information (FDA) Lipitor Detailed Consumer Information (PDR) Lipitor Advanced Consumer (Micromedex) - Includes Dosage Information Lipitor MedFacts Consumer Leaflet (Wolters Kluwer) Lipitor Consumer Overview
Lipitor
Generic Name: atorvastatin (a TOR va sta tin)
Brand Names: Lipitor
What is atorvastatin?
Atorvastatin is in a group of drugs called HMG CoA reductase inhibitors, or "statins." Atorvastatin reduces levels of "bad" cholesterol (low-density lipoprotein, or LDL) and triglycerides in the blood, while increasing levels of "good" cholesterol (high-density lipoprotein, or HDL).
Atorvastatin is used to treat high cholesterol, and to lower the risk of stroke, heart attack, or other heart complications in people with type 2 diabetes, coronary heart disease, or other risk factors.
Atorvastatin is used in adults and children who are at least 10 years old.
Atorvastatin may also be used for other purposes not listed in this medication guide.
What is the most important information I should know about atorvastatin?
You should not take atorvastatin if you are lipitor recommended dosage to lipitor recommended dosage if you are pregnant or breast-feeding, or if you have liver disease. Lipitor is ≥98% bound to plasma proteins. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Lipitor can lower the risk for heart attack or stroke in patients with diabetes and risk factors such as: eye problems, kidney problems, smoking, or high blood pressure. Tell your doctor about all medications you use. After randomization, patients were treated for 16 weeks with either Lipitor 10 mg per day or a fixed dose of the comparative agent (Table 7). Lipitor can lower the risk for heart attack or stroke in patients with diabetes and risk factors such as: eye problems, kidney problems, smoking, or high blood pressure. This effect may be worse if you take it with alcohol or certain medicines. Patients were mainly male (81%), white (99%) with an average age of 61.7 years, and an average LDL-C of 121.5 mg/dL at randomization; 76% were on statin therapy.
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