lipitor side effects ed
17.1 Muscle Pain All patients starting therapy with Lipitor should be advised of the risk of myopathy and told to report promptly any unexplained muscle pain, tenderness, or weakness. 8.5 Geriatric Use Of the 39,828 patients who received Lipitor lipitor side effects ed clinical studies, 15,813 (40%) were ≥65 years old and 2,800 (7%) were ≥75 years old. Metabolism: Lipitor is extensively metabolized to ortho- and parahydroxylated derivatives and various beta-oxidation products. Drug therapy is recommended as an adjunct to diet when the response to a diet restricted in saturated fat and cholesterol and other nonpharmacologic measures alone has been inadequate. Women who may become pregnant should use effective birth control while taking Lipitor. Patients who develop increased lipitor side effects ed levels should be monitored until the abnormalities resolve. Your doctor may prescribe it along with a special diet if your blood cholesterol or triglyceride level is high and you have been unable to lower your readings by diet alone. Male rats given 100 mg/kg/day for 11 weeks prior to mating had decreased sperm motility, spermatid head concentration, and increased abnormal sperm. Although food decreases the rate and extent of drug absorption by approximately 25% and 9%, respectively, as assessed by Cmax and AUC, LDL-C reduction is similar whether Lipitor is given with or without food. The drug generally begins working within lipitor side effects ed weeks. Or go to lipitor side effects ed nearest emergency room. For an even greater cholesterol-lowering effect, your doctor may prescribe Lipitor along with a different kind of lipid-lowering drug such as cholestyramine or colestipol. Adverse Reaction* Any dose N=8755 10 mg N=3908 20 mg N=188 40 mg N=604 80 mg N=4055 Placebo N=7311 Nasopharyngitis 8.3 12.9 5.3 7.0 4.2 8.2 Arthralgia 6.9 8.9 11.7 10.6 4.3 6.5 Diarrhea 6.8 lipitor side effects ed 6.4 14.1 5.2 6.3 Pain in extremity 6.0 8.5 3.7 9.3 3.1 5.9 Urinary tract infection 5.7 6.90 6.4 8.0 4.1 5.6 Dyspepsia 4.7 5.9 3.2 6.0 3.3 4.3 Nausea 4.0 3.7 3.7 7.1 3.8 3.5 Musculoskeletal pain 3.8 5.2 3.2 5.1 2.3 3.6 Muscle Spasms 3.6 4.6 4.8 5.1 2.4 3.0 Myalgia 3.5 3.6 5.9 8.4 2.7 3.1 Insomnia 3.0 2.8 1.1 5.3 2.8 2.9 Pharyngolaryngeal pain 2.3 3.9 1.6 2.8 0.7 2.1 * Adverse Reaction ≥ 2% in any dose greater than placebo Other adverse reactions reported in placebo-controlled studies include: Body as a whole: malaise, pyrexia; Digestive system: abdominal discomfort, eructation, flatulence, hepatitis, cholestasis; Musculoskeletal system: musculoskeletal pain, muscle fatigue, neck pain, joint swelling; Metabolic and nutritional system: transaminases increase, liver function test abnormal, lipitor side effects ed alkaline phosphatase increase, creatine phosphokinase lipitor side effects ed hyperglycemia; Nervous system: nightmare; Respiratory system: epistaxis; Skin and appendages: urticaria; Special senses: vision blurred, tinnitus; Urogenital system: white blood cells urine positive. Gastrointestinal Gastrointestinal side effects have been the most commonly reported. Following discontinuation of atorvastatin, the patient experienced significant clinical improvement with only mild residual aponeurotic ptosis after 2 months. Patients should be advised about substances they should not take concomitantly with atorvastatin involving 8,888 subjects (age range 26–80 years, 19% women; 99.3% Caucasians, 0.4% Asians, 0.3% Blacks, 0.04% other) treated with Lipitor 80 mg/day (n=4439) or simvastatin 20–40 mg daily (n=4449), there was no difference in the overall frequency of adverse reactions or serious adverse reactions between the treatment groups during a median follow-up of 4.8 years. Keep Lipitor and all medicines out of the reach of children.
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