lipitor side effects feet

If you suspect an overdose of Lipitor, seek medical attention. Patients who require a large reduction in LDL-C (more than 45%) may be started at 40 mg once daily. Visit your doctor regularly. Atorvastatin is only part lipitor side effects feet a complete program of treatment that also includes diet, exercise, and weight control. Lipitor can lower the risk for heart attack, stroke, certain types of heart surgery, and chest pain in patients who have heart disease or risk factors for heart disease such as: age, smoking, high blood pressure, low HDL-C, heart disease in the family. passing brown or dark-colored urine. Musculoskeletal HMG-CoA reductase inhibitors (statins) have been associated with rare cases of severe myopathy and rhabdomyolysis, accompanied by increases in creatine kinase, myoglobinuria, proteinuria, and renal failure. Five of the 29 patients had absent LDL-receptor function. Dosage Forms and Strengths White, elliptical, film-coated tablets containing 10, 20, 40, and 80 mg atorvastatin calcium. Its structural formula is: Atorvastatin calcium is a white to off-white crystalline powder that is insoluble lipitor side effects feet aqueous solutions of pH 4 and below. Drugs like Lipitor have occasionally been known to damage muscle tissue, so be sure to tell your doctor immediately if you notice any unexplained muscle tenderness, weakness, or pain, especially if you also have a fever or feel sick. REFERENCES 6.1 Clinical Trial Adverse Experiences Because clinical trials are conducted under widely varying conditions, the adverse reaction rates observed in the clinical studies of a drug cannot be directly compared to rates lipitor side effects feet the clinical trials of another drug and may not reflect the rates observed in clinical practice. The long-term efficacy of Lipitor therapy in childhood to reduce morbidity lipitor side effects feet mortality in adulthood has not been established. 274/2366, 11.6%) and increased the incidence of hemorrhagic stroke (55/2365, 2.3% vs. You have a higher chance for muscle problems if you are taking certain other medicines with Lipitor. Keep a list of them with you to show your doctor and pharmacist. Patients should also be advised to inform other healthcare professionals prescribing a new medication that they are taking Lipitor. The most common adverse experiences observed in both groups, regardless of causality assessment, were infections. Do not take Lipitor if it has been more than 12 hours since you missed your last dose. Do not start a new medication without telling your doctor. Where can I get more information? Your pharmacist can provide more information about lipitor side effects feet keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for lipitor side effects feet indication prescribed. Every effort has been made to ensure that the information provided by Cerner Multum, Inc. 17.2 Liver Enzymes It is recommended that liver function tests be performed prior to and at 12 weeks following both the initiation of lipitor side effects feet and any elevation of dose, and periodically (e.g., semiannually) thereafter. Mean Percentage Change From Baseline at Endpoint (Double-Blind, Randomized, Active-Controlled Trials) Treatment Non-HDL-C/ (Daily Dose) N Total-C LDL-C Apo B TG HDL-C HDL-C Study 1 Lipitor 10 mg 707 -27* -36* -28* -17* +7 -37* Lovastatin 20 mg 191 -19 -27 -20 -6 +7 -28 95% CI for Diff† -9.2, -6.5 -10.7, -7.1 -10.0, -6.5 -15.2, -7.1 -1.7, 2.0 -11.1, -7.1 Study 2 Lipitor 10 mg 222 -25‡ -35‡ -27‡ -17‡ +6 -36‡ Pravastatin 20 mg 77 -17 -23 -17 -9 +8 -28 95% CI for Diff† -10.8, -6.1 -14.5, -8.2 -13.4, -7.4 -14.1, -0.7 -4.9, 1.6 -11.5, -4.1 Study 3 Lipitor 10 mg 132 -29§ -37§ -34§ -23§ +7 lipitor side effects feet Simvastatin 10 mg 45 -24 -30 -30 -15 +7 -33 95% CI for Diff† -8.7, -2.7 -10.1, -2.6 -8.0, -1.1 -15.1, -0.7 -4.3, 3.9 -9.6, -1.9 *   Significantly different from lovastatin, ANCOVA, p ≤0.05 †   A negative value for the 95% CI for the difference between treatments favors Lipitor for all except HDL-C, for which a positive value favors Lipitor.

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