
During the first three years of life, the serum total- or free- T4 should be maintained at all times in the upper half of the normal range. If your dose is different, do not change it unless your doctor tells you to do so. The amount of medicine that you take depends on the strength of the medicine. 6 Aluminum Lake, FD&C Blue No. Thomson Reuters Healthcare and Drugs.com make no representation or warranty as to the accuracy, reliability, timeliness, usefulness or completeness of any thyroid synthroid alternative the information contained in the products. Short-term administration of large doses of glucocorticoids may decrease serum T3 concentrations by 30% with minimal change in serum T4 levels. Levothyroxine sodium should not be used in the treatment of male or female infertility unless this condition is associated with hypothyroidism. Therefore, it is recommended that patients receiving levothyroxine sodium be given the minimum dose necessary to achieve the desired clinical and biochemical response. thyroid synthroid alternative
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1 D&C RED NO. Synthroid tablets should be protected from light and moisture. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Synthroid is also used to treat or prevent goiter (enlarged thyroid gland), which can be caused by hormone imbalances, radiation treatment, surgery, or cancer. Pituitary TSH Suppression In the treatment or prevention of various types of euthyroid goiters (see WARNINGS thyroid synthroid alternative PRECAUTIONS), including thyroid nodules (see thyroid synthroid alternative and PRECAUTIONS ), subacute or chronic lymphocytic thyroiditis (Hashimoto's thyroiditis), multinodular goiter (see WARNINGS and PRECAUTIONS) and, as an adjunct to surgery and radioiodine therapy in the management of thyrotropin-dependent well-differentiated thyroid cancer. For patients who have recently initiated levothyroxine therapy and whose serum TSH has normalized or in patients who have had their dosage or brand of levothyroxine changed, the serum TSH concentration should be measured after thyroid synthroid alternative weeks. Check blood sugar levels closely. Dosing adjustments are based on an assessment of the individual patient's clinical and laboratory parameters (see PRECAUTIONS - Laboratory Tests). The initial dose of levothyroxine varies with age and body weight (see DOSAGE AND ADMINISTRATION - Table 3). Drug-Laboratory Test Interactions Changes in TBG concentration must be considered when interpreting T4 and thyroid synthroid alternative values, which necessitates measurement and evaluation of unbound (free) hormone and/or determination of the free T4 index (FT4I). 6 Product Characteristics Color YELLOW Score 2 pieces Shape ROUND Size 7mm Flavor Imprint Code Synthroid;100 Contains Packaging thyroid synthroid alternative NDC Package Description Multilevel Packaging 1 0074-6624-13 100 TABLET In 1 BOTTLE None 2 0074-6624-19 1000 TABLET In 1 BOTTLE None 3 0074-6624-11 10 BLISTER PACK In 1 BOX, UNIT-DOSE contains a BLISTER PACK 3 10 TABLET In 1 BLISTER PACK This package is contained within the BOX, UNIT-DOSE (0074-6624-11) Marketing Information Marketing Category Application Number or Monograph Citation Marketing Start Date Marketing End Date NDA NDA021402 07/24/2002 Synthroid levothyroxine sodium tablets tablet Product Information Product Type HUMAN PRESCRIPTION DRUG NDC Product Code (Source) 0074-6594 Route of Administration ORAL DEA Schedule Active Ingredient/Active Moiety Ingredient Name Basis of Strength Strength LEVOTHYROXINE SODIUM (LEVOTHYROXINE) LEVOTHYROXINE SODIUM 88 ug Inactive Ingredients Ingredient Name Strength ACACIA LACTOSE MONOHYDRATE MAGNESIUM STEARATE POVIDONE TALC FD&C BLUE NO. Regardless of the indication for use, careful dosage titration is necessary to avoid the consequences of over- or under-treatment. Thyroid hormones cross the placental barrier to some extent as evidenced by levels in cord blood of athyreotic fetuses being approximately one-third maternal levels. Do not share it with other people. It should not be used to treat obesity or weight problems. It is very important to take Synthroid with a full glass (8 ounces) of water. Concomitant use of these agents impairs the compensatory increases in clotting factor synthesis. Synthroid is in the FDA pregnancy category A. The adequacy of therapy is determined by periodic assessment of appropriate laboratory tests and clinical evaluation.
Cardiovascular Cardiac function was evaluated in twenty patients requiring TSH suppression for either thyroid goiter or following thyroidectomy and radioactive iodine therapy for thyroid cancer and in twenty age- and sex-matched controls. What should I avoid while taking levothyroxine? Do not change brands or change to a generic levothyroxine drug product without first asking your doctor. Ask your health care provider if Synthroid may interact with other medicines that you take. Other Associated Medical Conditions Infants with congenital hypothyroidism appear to be at increased risk for other congenital anomalies, with cardiovascular anomalies (pulmonary stenosis, atrial septal defect, and ventricular septal defect) being the most common association. They include the following: General fatigue, increased appetite, weight loss, heat intolerance, fever, excessive sweating; Central nervous system headache, hyperactivity, nervousness, anxiety, irritability, emotional lability, insomnia; Musculoskeletal tremors, muscle weakness; Cardiovascular palpitations, tachycardia, arrhythmias, increased pulse and blood pressure, heart failure, angina, myocardial infarction, cardiac arrest; thyroid synthroid alternative dyspnea; Gastrointestinal diarrhea, vomiting, abdominal cramps and elevations in liver function tests; Dermatologic hair loss, flushing; Endocrine decreased bone mineral density; Reproductive menstrual irregularities, impaired fertility. Skip the missed dose if it is almost time for your next scheduled dose. This is usually temporary. Tell your doctor if you have trouble swallowing. Synthroid Dosage and Administration General Principles The goal of replacement therapy is to achieve and maintain a clinical thyroid synthroid alternative biochemical euthyroid state. Even if you feel well, you may still need to thyroid synthroid alternative this medicine every day for the rest of your life to replace the thyroid hormone your body cannot produce. Delays in diagnosis and institution of therapy may have deleterious effects on the child's intellectual and physical growth and thyroid synthroid alternative Acute Massive Overdosage This may be a life-threatening emergency, therefore, symptomatic and supportive therapy should be instituted immediately. Seizures have occurred in a child ingesting 18 mg of levothyroxine. Levothyroxine sodium is contraindicated if the serum TSH is already suppressed due to the risk of precipitating overt thyrotoxicosis (see CONTRAINDICATIONS - WARNINGS and PRECAUTIONS).